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We also examined DAF-16::GFP subcellular localization in the intestinal cells of the various strains, as previous studies showed that DAF-16::GFP is localized to the nucleus of the germline-less worms 34

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Post-Translational Modifications (PTMs): Many therapeutic peptides undergo PTMs (e.g., amidation, glycosylation) that impact their biological activity

350,351 Loss-of-function mutations in Parkin (PARK2), an E3 ubiquitin ligase, underlie autosomal recessive Parkinsons disease